Thinking with your body, thinking with your mind

I’m too jetlagged to do this justice, but it’s an intriguing look at the way we solve 3-D problems with, and without, using our hands to work out solutions.

http://www.sciencedaily.com/releases/2011/06/110602111448.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fmind_brain+%28ScienceDaily%3A+Mind+%26+Brain+News%29

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News flash: Dementia is confusing & doctors should communicate

I can’t resist candidates for the Dept. of the Blith. Obv.: Many geriatric patients receive an incorrect dementia diagnosis. 

The final diagnosis was determined by postmortem autopsies examining structures and changes in the brain, which are pretty definitive.

Most dementias are currently incurable, and only some can even be managed. So why does this matter?
Two reasons: the clinical and the academic — which is ultimately clinical, too. 
Firstly — and I’m speaking as someone who has skirted dementia myself — if anything can be done to mitigate this hideous state, it should be done. Correct diagnosis improves your chances of getting appropriate care. 
Secondly, incorrect diagnoses screw up the data. How can we evolve our understanding, improve diagnostic criteria, develop more effective treatment, and work on actual cures, if we aren’t clear about what we’re working with and how it plays out?
What’s lovely and touching about this is, the researchers truly believed that correct diagnoses were much more common, and that the communications between the neurology department and the geriatric psychiatry clinic were better than they were … and that they changed their stance dramatically in response to their findings. 
Knowing how cautiously physician researchers normally phrase recommendations, and how neutral and respectful Swedes prefer to be, the researcher’s closing remarks sound like a passionate cry from the heart. It’s really moving. 
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Numeric literacy, mental integrity, and fun with ferrets

Most people get confused when faced with an article about medicine, or any kind of complex science. Because people with extremely expensive educations wrote that stuff, then other people figure (at some level below common sense) that the study’s authors must be fundamentally superior.

Education is not the same as intelligence.
Intelligence is not the same as sense.
Sense is not the same as integrity.

I come from a highly educated family. (‘Nuff said.) Growing up in the context of good education really made it clear that people are people, regardless of the letters after their names. Degrees simply mean that someone can work hard on their own behalf; they’re no guarantee of logic or brilliance. It’s never wise to subvert common sense in favor of education.

So, if you’re one of the majority who doesn’t have alphabet soup after your name, give yourself some credit as you read these things.

There are a few simple principles that can help you dissect a study with reasonable confidence:

  • Question assumptions (& listen to your eyebrows.)
  • When the question makes no sense, you don’t have to accept the answer.
  • If it seems stupid, it probably is.
  • Don’t ignore the man behind the curtain.

A Furry Example of Fuzzy Logic
The article cited below is precious … A delicious exercise in mental pretzel-ry designed to reduce the average brain to cottage cheese. It’s easy to unravel if you hang onto your common sense and don’t let go, because your brain is not average.
Ready? Here it is.

  1. The title of the article linked below proclaims that researchers have proven that Topic A is bogus.
  2. The researchers’ summary says no such thing. It states that they’ve proven that your belief in Topic A should be much greater if you do believe in it or much less if you don’t; doesn’t matter which.
  3. Then the researchers state that that finding, itself, doesn’t matter, because they personally don’t believe in Topic A, can’t think of anything in its favor, and that you should agree with them — regardless of their own findings — simply because they said so.  (A fairly common conclusion.)

Let’s pause to regroup, since this is enough to make most people tear their hair and gnaw the furniture. That tends to kill the punchline.

Backing up the train of thought to the beginning…


Pick something that there’s some disagreement about. For the sake of clarity, choose something not too emotional, like, “Do ferrets make good pets?” Pretend that’s Topic A.

You’ve already thought of ideas that support this and ideas that don’t, and you probably already know whether you, personally, would like having a ferret as a pet.

Have you ever, in your most random moments, picked a percentage or a ratio to indicate how much you would, or wouldn’t, like to have a ferret as a pet, with nothing to compare it to? I mean, is there any value to the idea of doing so? How odd is it to assume that people would?

TIP: Question assumptions. If your brain — or the skin on your forehead — starts to squirm, it’s a good clue that there’s an unexamined assumption waiting to jump up and trip you. Stop and check. 

Liking pet ferrets is simple: you either like them (a little or a lot), you don’t like them (a little or a lot), or you decide you don’t know enough to have an opinion. That last option isn’t even available here, but it’s very common.

If you have an opinion about ferrets as pets, doesn’t its extent depend on external forces — whether you’ve known pet ferrets, whether their owners were responsible, whether it was a nice ferret or a real brat?

And wouldn’t the appeal of keeping/getting rid of a pet ferret depend on whether there’s a pet store stocking ferrets and ferret supplies, what your lease says about pets, whether or not your housemate can ferret-sit while you’re hiking the Camino de Santiago, whether your veterinarian can help you surrender an unwanted ferret? And don’t these circumstances themselves change, from place to place and time to time?

So how can you assign an absolute percentage to your opinion about whether ferrets make good pets? How surprised would you be if anyone asked you to do so?

And, really… Why would you? Do you assign a percentage to how much you dis/like strawberries, the color blue, or Sarah Palin? Or don’t you use value words instead — love, like, can’t stand?

Unless most (rather than very few) of you think of your preferences in numeric terms, then the very question the researchers are trying to answer is fantastical. Pure silliness.

TIP: You don’t have to accept an answer, if the question itself makes no sense. 

Moreover, the way they processed the data doesn’t change your answer; it indicates that your beliefs should be far stronger, whatever they are.

They’re saying that, if you would like a ferret as a pet, you should be on your knees at the pet shop, weeping with longing — or, if you already have one, should be emitting a constant stream of happy little noises as you snuggle your ferret at work, on the bus, everywhere, all the time.

If you would not like a pet ferret, you should be packing to move so you can stay as far away as possible from anything long and furry or even vaguely ferretlike — or just blow up all the ferret-friendly pet shops where you live.

TIP: Just because someone with a very expensive education says it, doesn’t necessarily make it so. If it seems stupid, it probably still is.

Contrary to the title of the article, the results tell you: don’t change  your position, just become more extreme about it. That’s their conclusion.

Isn’t that helpful? Just what we need: debates that are even more shrill, spittle-flecked and unreasoning.

TIP: Repeat prior tip… Really stupid.
In light of the decisions that led up to this conclusion and the anti-intellectual nature of the outcome, do you think this makes sense? 

And, clearly following their own advice, the scientists themselves pick a side and pronounce that they don’t like pet ferrets and that you shouldn’t like them either.

Why?

Because they don’t understand how anyone could like pet ferrets and BTW other scientists in vaguely pertinent fields don’t know enough to prove how pet ferrets can possibly be desirable.

Therefore (stretching the metaphor), given this massive ignorance on the part of so many highly-educated people, ferrets are obviously terrible pets and all of them should be gassed.



…WHAT??…

SUMMARY:

This is not a terrible study and it was not done by stupid people. They just left their mental integrity in their other jeans, and that happens a lot.

Why on earth…? Because we all have assumptions and agendas.

Science aims to clear that out, but it’s done by live humans with organs and mortgages, so their objectivity is pretty hit-and-miss.

When reading science articles, be open to hidden agendas while you look for the facts.  For better or worse, they go together. You might as well notice both.

Scientists are often very obvious about using big words to say silly things, and if you can step aside from feeling intimidated, it’s surprising how obvious they are.

The problems here are common problems:

  • Point 1. Article’s title misrepresents the outcome of the study.
    I usually read an article at least twice before making up my mind.
    I read it through, then start again at the title.  How accurate is it?
    If the title isn’t fairly accurate, I know someone’s got an intrusive agenda.
  • Point 2. Outcome doesn’t make sense.
    It says you should believe either more than you do, or less than you do, but it doesn’t matter which.  How to do so is not mentioned (for good reason.)
    I usually look over the details of an article three or four times, to give the facts time to sift together in my mind.
    When I feel my brow wiggling at something, I stop and look again. I trust my good sense more than I trust my education.
    Figuring out crappy data just requires you to assume you’re not an idiot, even if you don’t know the field. 
    Don’t think badly of the scientists, just assume they have their own sets of human flaws.  It’s a safe assumption!
  • Point 3. Conclusion goes against the findings.
    In any case, DON’T believe in Topic A, because the researchers have made up their minds on the basis of their ignorance, and screw their data anyway.
    Continue to assume you’re not an idiot, as you read the conclusion.  It’s that simple.
    Then compare it, again, to the title and to the facts.
    If something doesn’t add up, you know there’s agenda going on.

These particular scientists intended to prove that their statistical method was better than existing methods. Given all the logical problems surrounding their efforts, I think they blew it, but I’m not a statistician.
CLUE:
The topic of this study was ESP.

As my relentlessly rational, very prescient Dad once said when I asked him whether his use of ESP was irrational, “It would be irrational to ignore the evidence of my own experience. It’s highly consistent for me, even though most people can’t do it, or can’t do it very well. But just because they can’t use this valuable tool, does that mean I shouldn’t?  That wouldn’t be very clever!”

Dad was very clever. (…And for the record, he did foresee his own end.)

Let’s step over to another, less-emotional metaphor to think about studying this subject.
Imagine that most people are basically color blind, but a few can see some color.  Anyone who can see beyond the greyscale is not going to get much credit, but there are enough of them to make the rest wonder.

However, since the colorblind are looking for proof of color with instruments that see only luminance, but cannot see color even as tone or hue, they probably won’t have much luck proving something that they don’t understand, can’t use, and don’t believe in anyway. (…But they can sure get snarky, trying.)

TIP: Don’t ignore the man behind the curtain. Think for yourself … And try to remember, especially if you’re in a position of respect, that you don’t necessarily have the right to think for others. 

Today’s unbelievably fatuous truism, which everyone always forgets anyway:  Other people are not you. Only you are. Honor that, and things go better.

THE POINT IS:
In the end, everyone has to pursue their own logic, account for their own experiences, and come to their own conclusions.

What science is supposed to offer is a crystalline view of measurable and provable data. It doesn’t help if the scientists pick up a hammer and smash the crystal when presenting it to public view.

As I know all too well, education is not the same as intelligence; intelligence is not the same as sense; sense is not the same as integrity.

Read studies for yourself.  Practice makes perfect: the more you do it, the easier it gets, and the more accurate (and potentially shocking!) your understanding becomes.

Jump in here and comment on your own experiences. I’d love to hear from you about your adventures with this.

THE STUDY:

http://www.sciencedaily.com/releases/2011/05/110518080059.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fmind_brain+%28ScienceDaily%3A+Mind+%26+Brain+News%29

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Everything has side-effects

This replaces “The Dominance of Duh,” a diatribe written in a haze of detox from overmedication. This post should be more useful.

“First, do no further harm.”

It’s the most important treatment guideline there is.

Why is that so relevant? Because Nature doesn’t give the body a free pass, just because the poison comes with a prescription. Physics and chemistry are not impressed by education; they do exactly what they are supposed to do, regardless of who’s watching them… Or failing to.

Therefore, prescriptions don’t alter the nature of what’s being prescribed. Every assault on the body — however therapeutic it’s intended to be — triggers a response involving the nerves, inflammation, and immune system. Medications affect the liver and kidneys, and probably the intestinal system as well.

That’s a lot to affect.

How do you deal with this in the real world, as a real person with real conditions requiring real medication?

Well, good friends help. So does communication. Here’s why:

Your doctor/practitioner is supposed to do a risk-benefit analysis of each drug prescribed. Some take this more seriously than others, some weigh the risks differently, and each practitioner has a unique idea of what’s really important in the first place. It’s good to be aware of your practitioner’s priorities and beliefs, so that their decisions make more sense to you, and you can be better aware of what to ask about or follow up on.

Communication: Get the lowdown on the treatment from your doctor, your pharmacist, your nurse friends. It can be confusing at first since everyone has their own ideas, but the common themes (and common concerns) will emerge, giving you something to look into more closely. Also, they can tell you what terms to use when you go to look it up online.

Good friends: One reason we have friends is so we don’t have to hold everything in our own heads: we can talk things over with them, and then go back for reminders. Another is because they can help us clarify our thinking, and if your meds can make you a bit confused, that’s essential! It’s important to have friends who can tell you when you’re a mess, and maybe it’s time to get your meds re-evaluated.

Need to get your meds re-evaluated? That brings us back to communication, and talking things over with your doctor. It’s a perfectly reasonable thing to ask, so feel free to: medically speaking, it’s good practice to do this periodically. Bring a friend to the appointment, if that would help you discuss it.

Three more things you can do, essential to health: drink plenty of water, eat plenty of produce, and get a bit of fresh air every day. These help your body clear out the excess, keep your natural detox systems working, and provide your body with the building blocks for recovering from the chemicals — either the added chemicals of medication, or the stress chemicals your body releases around treatments and procedures, or both.

Being a patient is a tough job. We have to trust our beings to people who aren’t us, and that entails a certain amount of risk. It’s EXTREMELY easy to blame doctors for screwing up, but when all is said and done, we own our share of responsibility in that relationship.

So talk to your doctor. Talk to your friends. Drink up and eat your greens. Now let’s take a nice walk …

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Putting the "con" in mitochondria, the "funk" in dysfunction

Mitochondria (from the Greek, meaning “string grain” — yeah, it’s lame, but it sounds good in Greek) are independent little one-celled organisms that live inside your cells and make energy for them. If you ever studied the ATP cycle (also called the Krebbs cycle or the citric acid cycle, depending on where you went to school and how deeply they went into it), then you should know that this is where the ATP cycle takes place.

Without mitochondria, you have no way of converting food into energy.

When you were being conceived, half your cells’ genes came from your mother and half from your father. All of the other stuff that goes inside a cell came from your mother. This includes the mitochondria. (This is why mitochondrial DNA is used to track maternal inheritance: it always comes down the female line.) Your mother’s cell hosts conception, just as (normally) your mother’s body hosts gestation.

Mitochondria have a fairly smooth outer layer and a deeply-rumpled inner layer. Most of the action happens inside the rumpled layer. This is where the ribosomes, most of the fluids and loose protein, and the ATP-making particles hang out.

Cells, including mitochondria, need various proteins to do their work with. Large proteins get carefully handed from the outside world, through the outer layer of the mitochondrion (singular of “mitochondria” — sorry, it’s still Greek), then into the inner layer.

If the smooth outer layer is damaged, this makes this transfer process screw up, and the inner layer gets disrupted, ripping up the cell. Granules and nucleic acids all over the place. Bang goes that ATP production.

Those are some busted mitochondria.

This kind of damage happens in response to certain kinds of toxins (including certain medications for AIDS and all psychoactives — including antidepressants and pain medications, which seems especially mean!), occasionally from genetic disturbance, and occasionally as a consequence of illness — or nerve injury and its complications.

Mitochondrial dysfunction has been repeatedly and profoundly linked to neurogenerative diseases like Alzheimer’s and Parkinson’s; cell-metabolism problems like heart disease, insulin resistance and type II diabetes; and several diseases often mistaken for CRPS.

Not surprisingly, symptoms of mitochondrial dysfunction are the worst in tissues that use the most energy and have the largest number of mitochondria per cell: nerves, muscles, brain.

Recently, it has been strongly associated with CRPS. And the cherry on top: it plays a vital role in neuroplasticity, or the way your nerves and brain change — for better or worse.

Hell-o, “pain-brain.” We thought we knew ya!

Knowing why it’s so damnably exhausting to walk a mile, when it used to be fun — fun! — to run 3, is a bit of a relief. First question that leaps to my mind: How do I fix ’em? How do I give them what they need to get better and protect themselves?  The answer seems simple: antioxidants are what’s needed to prevent and repair that damage (good explanation of that here) to the walls of the mitochondrial cell.  Mitochondria are both the biggest makers of reactive oxygen species and the biggest scavengers of them, so of course it makes sense that that’s exactly the kind of help they need when they can’t keep up.

Downing antioxidants by the bucketful is one way to get them in. Intriguing for three reasons:

  • Taking moderate amounts of the antioxidant Vitamin C after surgery hugely reduces your chances of getting CRPS. (Upper limb and lower limb surgeries were studied.)
  • There’s some indication that Vitamin K may help combat the progress of CRPS.
  • Taking antioxidants is pretty easy: delicious food, accessible pills, not bad.

Kind of depressing for one simple reason: it’s iffy whether, once you’ve got the disease process going, the antioxidants can get where they’re needed and save your poor beleaguered mitochondria. … Having said that, I notice that the writers of that article seem to be trying to sell something, and that makes me very suspicious of their conclusions.

Next, I’ll offer suggestions for patients, suggestions for clinicians, and then wind this up with a foray into the question of whether mitochondrial issues have a genetic component, like being X-linked — the way a cat’s fur color is! 

For people with CRPS — So what is a poor, confused CRPSer to do?

Two things that you hardly need reminding of:

  1. Trust your sense of your own body.
  2. Do what works for you.

Most antioxidants are not going to hurt you, without letting you know first (that is, make you nauseous or feel funny.) Take vitamin C in doses no larger than 500mg, since larger doses tend to trigger your gut to throw the C away. Go ahead and try stress-vitamins, co-enzyme Q-10, N-acetylcysteine, hair-skin-&-nails vitamins (these are really fat-soluble antioxidants) … try things, take what helps, and put aside the rest if they don’t do anything. Keep in mind that things change: what doesn’t work now might work later, and vice-versa.

Also, eat all the leafy greens you can get: seaweed snacks, Mom’s collard greens, kale krunchies, spinach salad, you name it. It’s amazing nerve food.

For antioxidant powerhouses, look for dark-red and dark-blue fruits: pomegranates, blueberries, red wine, chocolate (though some CRPS people have to avoid that for its nerve effects), mangosteen (my favorite fruit), cranberries, and so on.

Stay smart. Stay loose. Keep going.

For medical people — clinical takeaways:

Most treatment standards, particularly for CRPS, are based on science that’s over a decade old. They shouldn’t be changed blithely but they can certainly be improved. There is plenty of room for that.

The following points are intended as additions to the standards you follow for CRPS, as they are good guidelines for mitochondrial and neurologic support in a system compromised by CRPS.

  •  After any limb surgery, give Vitamin C 500 mg, QD or BID, for a couple weeks beforehand and 30-50 days after — or to metabolic tolerance, if that’s too much. Use a food-associated form for best uptake. This one intervention will reduce the risk of developing CRPS by 80%, according to the best current data.
  •  We assume your patients are taking an adequate multivitamin and are eating plenty of greens, dark fruits, and wholesome proteins. So make sure they are.  Direct them to food bank, food stamps or other food assistance as needed. Give recipes. (No kidding.)  2 benefits: better antioxidant uptake if taken with antioxidant-rich food, and increasing the patient’s own sense of agency/participation improves pain and affect.  (If you don’t believe in multivitamins, then get out of the supermarket/pharmacy and get some real ones.)
  •  Stress the antioxidant vitamins.  In acute CRPS, give water-soluble antioxidant vitamins in 1-3x the doses you’d give a healthy person.  Give fat-soluble antioxidants (A, D, E) up to 2x normal, testing levels as indicated.  Consider vitamin K inj.
  •  In cold/chronic CRPS, give water-soluble antioxidant vitamins in 3-5x the doses you’d give a healthy person (start at 2x and work up).  Give fat-soluble antioxidants (A, D, E) up to 2-4x normal, testing levels as indicated; consider weekly mega-dose D (as used in AIDS.)  Give vitamin K inj.  Check serum or urine levels as indicated, especially as we develop absorption disorders.
  •  Give “uber-antioxidants” like ubiquinone (co-Q 10), N-acetylcysteine, or glutathione. There are indications that these can provide substantial benefit — though again, not normally curative of chronic CRPS. They are impressive, especially for mitochondrial-dysfunction issues.

These ranges are empirical; if you can find the funding to do the science to develop more reliable ranges for this population, so much the better.

Adequate tissue oxygenation and perfusion can return substantial function and significantly reduce pharmacologic burden. Patients can demonstrate this, even where the data have not been published and peer reviewed. Therefore, use antioxidants rigorously and intelligently.

Image credit: http://www.vrp.com/antioxidants/-r-lipoic-acid-unique-mitochondrial-antioxidant-fights-premature-aging.  (Article’s not bad.)

Why all that anti-oxidation when the medical literature is not definitive?  2 reasons, which you ought to know for yourselves:

  1. Between the cortisol and systemic oxidative stresses, it can’t hurt and it will help something. You’ll see a distinct improvement in affect, activity, motivation and well-being when the dose is optimized, even if it can’t be expected to be curative.  Making your patient’s life more bearable is an essential part of your job.
  2. Let’s say this together, everyone: statistics mean nothing in the case of the individual.  Accepted, standardized medicine is what you start with, but, when your case is taking you out to the margins, you go to the margins, because that’s where your success is most likely to await.  

Keep in mind that doctors are not the only scientists interested in the human body.  Be prepared to look into other disciplines for leads when your own offers no good options.

Try Nursing, PT, Nutrition, Therapeutic Massage — you’ll realize that nobody knows more about soft tissue’s functional physiology in vivo than therapeutic massage science, and if nothing else, the exercise in intellectual flexibility might do you good.

The accepted style is very different, but the info they have is tremendous.

Forward-looking thoughts:

  • Consider infusing vitamin K into CRPS-damaged tissues. I would love to see studies on that.
  • Figure out how to deliver antioxidants in a targeted way. (Now! Please!) This would be a good way to save a lot of lives and end tons of misery.

… And for all curious people …

Let’s go back to mitochondria in reproduction. Kind of in an X-rated way, figuratively speaking.

We know that women have two X chromosomes. The Y chromosome is a stubby little object with hardly any data to use, unless you’re into color-blindness or hemophilia; this means women have quantities of extra data, which can have even more devastating effects (as in, Down syndrome.) So how to handle the extra genes?

Pick one. Simple as that.

Shortly after conception, when the cells are just dividing like mad and haven’t decided what to be yet, every single cell turns off one of its two X chromosomes; each of that cell’s daughter cells inactivates the same X chromosome. As the cells continue to multiply, then fill out, fold, bend around, and specialize, to become a whole, separate being, it means that X-linked traits appear in a mottled pattern throughout the body, as the two sets of daughter cells continue reproducing and passing on their particular X-activations.  Isn’t that curious?

As an especially decorative instance, cats’ hair color is an X-linked trait:

Cool, huh? Love her accent, too.

But this fact brings me to a serious question about mitochondrial disease. If mitochondria are sex-linked, is there a relationship between the X chromosome and mitochondrial expression? It seems improbable that there wouldn’t be, because mitochondria reside inside the cell, and the cell’s action is determined by the genes within it. The mitochondria had to have developed a special relationship with the X’s in the 23rd chromosomal pair, after all those millenia.

It’s generally accepted that mitochondrial diseases are due to toxification or to complex, multigenetic issues. Ok, fine. But what about mitochondrial vulnerabilities that don’t become pathologic until they are damaged in some other way? To what degree is toxification an issue related to X-activation? In other words, is mitochnodrial vulnerability related to vulnerabilities in the active X chromosome?

Is there a patchy characteristic to the early stages of mitochondrial destruction? — You know, the early stages of rare disorders, the time when it’s impossible to get a diagnosis because the doctors are all so busy chasing their own tails around your irrational symptoms and their own ignorance.

Is that initial “mottled” activity one reason why these diseases are so damn weird?

Link list:

Wikipedia’s entry on mitochondria is pretty good:
http://en.wikipedia.org/wiki/Mitochondria

On mitochondria and AIDS meds:
http://www.ncbi.nlm.nih.gov/pubmed/20818734
On mitochondria and pyschoactives:
http://www.ncbi.nlm.nih.gov/pubmed/18626887

Alzheimer’s Foundation:
http://www.alzfdn.org

Michael J. Fox’s Parkinson’s foundation:
http://www.michaeljfox.org/

United Mitochondrial Disease Foundation, listing diseases which are often mistaken for CRPS:
http://www.umdf.org/

Mitochondria and neuroplasticity:
http://www.ncbi.nlm.nih.gov/pubmed/20957078

A good rundown (so to speak) of antioxidants’ function:
http://www.ionizedwateronline.com/Antioxidants.html

Vitamin C around surgery.
Upper limb:
http://www.ncbi.nlm.nih.gov/pubmed/17606778
http://www.ncbi.nlm.nih.gov/pubmed/20224742
Lower limb:
http://www.ncbi.nlm.nih.gov/pubmed/19840748

Vitamin K and CRPS progression:
http://www.ncbi.nlm.nih.gov/pubmed/20378261

Getting antioxidants where they’re most needed. Ignore the shystering towards the end:
http://www.ncbi.nlm.nih.gov/pubmed/21422516

ALA and regeneration of Vitamin E:
http://www.vrp.com/antioxidants/-r-lipoic-acid-unique-mitochondrial-antioxidant-fights-premature-aging

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Re-Learning Aids

I originally created this blog as a place to digest articles on medicine and biomedicine — especially as they relate to real, live human beings of the kind who need to use medicine and biomedicine. After all, needing it means our systems are not quite normal.

I have a condition that punches holes in my memory and cognition. This means that, even though this biomedical stuff is meat and drink to me, I have to look up things that — with my old brain — I used to know like the back of my hand. (That is, the hand where the CRPS started, naturally.)

Really basic things, like the names of our handful of neurotransmitters, each with its many jobs; or the role of the pituitary gland and its intense relationship with … well, with every other regulatory part of the body.

So I’ll post a couple of tutorials on these subjects here, for both you and me to refer to at need. If I’m really clever, I’ll post them as pages which you can access easily; for now, I’ll be happy to get them up at all.

Soooo …. [drumroll, please]

Coming soon:
– A quick rundown on neurotransmitters, with interesting dietary notes.
– Tutorial on the Limbic-Hypothalamic-Pituitary-Adrenal axis.

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