This article discusses the role of the peptide CDB3 in modulating the specific calcium channel signals that transmit chronic pain:
This article says it’s a “novel” peptide, but last I heard, CDB3 was a cannabinoid, one of a couple hundred constituents derived from a medicinal plant cultivated for thousands of years, being researched by the likes of Prof. Robert Malamede in Colorado… For, among other things, specific & benign interference in calcium-channel signaling in pain pathways.
Let’s keep our signals clear, even if we want to muddle pain’s signals.